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Oprah has named her latest selection to her book club, choosing Middlesex by Jeffrey Eugenides. With that announcement the book has shot up the bestseller lists.

Publisher’s Weekly describes the novel’s storyline: “As the Age of the Genome begins to dawn, we will, perhaps, expect our fictional protagonists to know as much about the chemical details of their ancestry as Victorian heroes knew about their estates. If so, Eugenides (The Virgin Suicides) is ahead of the game. His beautifully written novel begins: “SpMiddlesex by Jeffrey Eugenidesecialized readers may have come across me in Dr. Peter Luce’s study, ‘Gender Identity in 5-Alpha-Reductase Pseudohermaphrodites.’ ” The “me” of that sentence, “Cal” Stephanides, narrates his story of sexual shifts with exemplary tact, beginning with his immigrant grandparents, Desdemona and Lefty. On board the ship taking them from war-torn Turkey to America, they married-but they were brother and sister. Eugenides spends the book’s first half recreating, with a fine-grained density, the Detroit of the 1920s and ’30s where the immigrants settled: Ford car factories and the tiny, incipient sect of Black Muslims. Then comes Cal’s story, which is necessarily interwoven with his parents’ upward social trajectory. Milton, his father, takes an insurance windfall and parlays it into a fast-food hotdog empire. Meanwhile, Tessie, his wife, gives birth to a son and then a daughter-or at least, what seems to be a female baby. Genetics meets medical incompetence meets history, and Callie is left to think of her “crocus” as simply unusually long-until she reaches the age of 14.”

“With a sure yet light-handed touch,” writes Booklist, “Eugenides skillfully bends our notions of gender as we realize, along with Cal, that although he has been raised as a girl, he is more comfortable as a boy. Although at times the novel reads like a medical text, it is also likely to hold readers in thrall with its affecting characterization of a brave and lonely soul and its vivid depiction of exactly what it means to be both male and female.”

Here’s an excerpt from Middlesex:

I was born twice: first, as a baby girl, on a remarkably smogless Detroit day in January of 1960; and then again, as a teenage boy, in an emergency room near Petoskey, Michigan, in August of 1974. Specialized readers may have come across me in Dr. Peter Luce’s study, “Gender Identity in 5-Alpha-Reductase Pseudohermaphrodites,” published in the Journal of Pediatric Endocrinology in 1975. Or maybe you’ve seen my photograph in chapter sixteen of the now sadly outdated Genetics and Heredity. That’s me on page 578, standing naked beside a height chart with a black box covering my eyes.

My birth certificate lists my name as Calliope Helen Stephanides. My most recent driver’s license (from the Federal Republic of Germany) records my first name simply as Cal. I’m a former field hockey goalie, long-standing member of the Save-the-Manatee Foundation, rare attendant at the Greek Orthodox liturgy, and, for most of my adult life, an employee of the U.S. State Department. Like Tiresias, I was first one thing and then the other. I’ve been ridiculed by classmates, guinea-pigged by doctors, palpated by specialists, and researched by the March of Dimes. A redheaded girl from Grosse Pointe fell in love with me, not knowing what I was. (Her brother liked me, too.) An army tank led me into urban battle once; a swimming pool turned me into myth; I’ve left my body in order to occupy others—and all this happened before I turned sixteen.

But now, at the age of forty-one, I feel another birth coming on. After decades of neglect, I find myself thinking about departed great aunts and -uncles, long-lost grandfathers, unknown fifth cousins, or, in the case of an inbred family like mine, all those things in one. And so before it’s too late I want to get it down for good: this rollercoaster ride of a single gene through time. Sing now, O Muse, of the recessive mutation on my fifth chromosome! Sing how it bloomed two and a half centuries ago on the slopes of Mount Olympus, while the goats bleated and the olives dropped. Sing how it passed down through nine generations, gathering invisibly within the polluted pool of the Stephanides family. And sing how Providence, in the guise of a massacre, sent the gene flying again; how it blew like a seed across the sea to America, where it drifted through our industrial rains until it fell to earth in the fertile soil of my mother’s own Midwestern womb.

Sorry if I get a little Homeric at times. That’s genetic, too…

Continue Reading Here

Eugenides also reads a portion of Middlesex at the Prague Writers Festival here:


Oprah also has a list of of book club questions for discussing Middlesex:

  1. Describing his own conception, Cal writes: “The timing of the thing had to be just so in order for me to become the person I am. Delay the act by an hour and you change the gene selection” (p. 11). Is Cal’s condition a result of chance or of fate? Which of these forces governs the world as Cal sees it?
  2. When Tessie and Milton decide to try to influence the sex of their baby, Desdemona disapproves. “God decides what baby is,” she says. “Not you” (p. 13). What happens when characters in the novel challenge fate?
  3. “All I know is this: despite my androgenized brain, there’s an innate feminine circularity in the story I have to tell” (p. 20). What does Cal mean by this? Is his manner of telling his story connected to the question of his gender? How?
  4. Calliope is the name of the classical Greek muse of eloquence and epic poetry. What elements of Greek mythology figure into Cal’s story? Is this novel meant to be a new “myth”?

More Book Club Questions


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